Device
COPA.S1

Part:BBa_K2826008:Design

Designed by: Huang Fangliang   Group: iGEM18_ASTWS-China   (2018-10-08)


copper sensor1


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    INCOMPATIBLE WITH RFC[25]
    Illegal AgeI site found at 898
    Illegal AgeI site found at 1010
  • 1000
    COMPATIBLE WITH RFC[1000]


Design Notes

The device contains a copperA promoter,a riboJ,a RBS,a RFP repoter and two terminator. This device will be used to detect copper in solution. The copA promoter is active in the presence of copper. RiboJ can reliably maintain relative promoter strengths. RiboJ helps reduce the leakage of copA promoter greatly. After adding copper ions, the expression of red-fluorescent protein increased steadily.

Source

Copper ion detection experiment experimental method:2.5 ml of LB solution was added with 2.5 ml of sterilized ultrapure water, and BBa_K2826013 broth was added to make a final concentration of 0.02 OD,cultured at 37 degrees on a shaker for 10 hours. 100 microliters of bacterial solution was taken every 2 hours to detect red fluorescence. When measuring wastewater, replace 2.5 ml of ultrapure water with 2.5 ml of waste water.

References